PIMOBENDAN

Descriptions

Biochem/physiol Actions

Pimobendan is an inotropic agent with a dual mechanism of action: it increases myocardial contractility by increasing calcium sensitization to troponin C and it promotes vasodilation by inhibiting phosphodiesterase III (PDE3). Pimobendan has been studied for treating heart failure and cardiomyopathy, primarily for veterinary uses.

Packaging

10, 50 mg in glass bottle

Specifications

Colour	white to beige
Quality Level	100
InChI key	GLBJJMFZWDBELO-UHFFFAOYSA-N
InChI	1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: 5 mg/mL, clear (warmed)
Form	powder
Assay	≥98% (HPLC)