PHENPROCOUMON

Descriptions

Biochem/physiol Actions

Phenprocoumon is a coumarin derivative that inhibits vitamin K and acts as a long acting oral anticoagulant. It was recently found to act synergistically with flutamide to modulate the stability of the androgen receptor (AR) and resensitize AR-mutant prostate cancer cells to flutamide.

Specifications

Colour	white to beige
InChI key	QNDUUBVQYBBRBW-UHFFFAOYSA-N
InChI	1S/C18H16O3/c1-2-13(12-8-4-3-5-9-12)16-17(19)14-10-6-7-11-15(14)21-18(16)20/h3-11,13,20H,2H2,1H3
Manufacturer	SIGMA-ALDRICH
Storage Temp.	2-8°C
Solubility	DMSO: 2 mg/mL, clear
Form	powder
Assay	≥97% (HPLC)