PF-06446846 HYDROCHLORIDE

PF-06446846 HYDROCHLORIDE

Stock Code: 3573834
Manufacturer Part No: PZ0374-25MG
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£702.00 (exc VAT) per 25MG
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Biochem/physiol Actions


PF-06446846 is a selective orally active PCSK9 inhibitor that appears to act by causing the ribosome to stall when synthesizing PCSK9. PCSK9 binds to the LDL receptor, preventing it from removing LDL cholesterol from the blood. PF-06446846 was found to reduce plasma PCSK9 and total cholesterol levels in rats.


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Pfizer is a registered trademark of Pfizer, Inc.


Sold for research purposes under agreement from Pfizer Inc.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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