PD184352, >=98% (HPLC)

PD184352, >=98% (HPLC)

Stock Code: 3573590
Manufacturer Part No: PZ0181-5MG
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£168.54 (exc VAT) per 5MG
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Biochem/physiol Actions


PD184352 (CI-1040) is a highly selective non-competitive inhibitor of MEK (MKK1; MAPK kinase) and the closely related MKK2. It has anti-cancer activity, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell lines.


Features and Benefits


This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Legal Information


Pfizer is a registered trademark of Pfizer, Inc.


Sold for research purposes under agreement from Pfizer Inc.


Other Notes


This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to tan
InChI keyGFMMXOIFOQCCGU-UHFFFAOYSA-N
InChI1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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