OGERIN NEGATIVE CONTROL
Biochem/physiol Actions
Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.
Packaging
5, 25 mg in glass bottle
Recommended products
The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here.
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | RVKAHYFWSKSSQQ-UHFFFAOYSA-N |
| InChI | 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22) |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: 20 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
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