NSC23766 TRIHYDROCHLORIDE

NSC23766 TRIHYDROCHLORIDE

Stock Code: 3574288
Manufacturer Part No: SML0952-25MG
Order Now for 5 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Application


NSC23766 trihydrochloride has been used as a ras-related C3 botulinum toxin substrate 1 (RAC1) inhibitor.


Biochem/physiol Actions


NSC23766 is an inhibitor of Rac1, a Rho-family GTPase. The compound blocks activation by the guanine nucleotide exchange factors Trio and Tiam1, but does not affect interactions with RhoA or Cdc42. NSC23766 blocks ADP-mediated platelet aggregation. Inhibition of Rac1 by NSC23766 restores sensitivity to trastuzumab by restoring down-regulation of ErbB2.


Features and Benefits


This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityH2O: 10 mg/mL, clear
Formpowder
Assay≥97% (HPLC)

There are no downloads for this product.