Methylstat, >=98% (HPLC)

Methylstat, >=98% (HPLC)

Stock Code: 3574049
Manufacturer Part No: SML0343-5MG
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£238.18 (exc VAT) per 5MG
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Biochem/physiol Actions


Methylstat is an inhibitor of the Jumonji C domain-containing histone trimethyl demethylases (JHDMs). Methylstat inhibits the activity of JMJD2C (IC50 = 4.3 µM), with similar potency against JMJD2E and JMJD3. The compound has poor activity against dimethyl demethylases, and does not inhibit class I or II HDACs. Methylsat blocks proliferation of the esophageal carcinoma cell line KYSE150 with an IC50 value of 5.1 µM.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyMUJOCHRZXRZONW-FOCLMDBBSA-N
InChI1S/C28H31N3O6/c1-36-27(33)16-15-26(32)31(35)18-5-4-17-29-19-21-11-13-22(14-12-21)20-37-28(34)30-25-10-6-8-23-7-2-3-9-24(23)25/h2-3,6-16,29,35H,4-5,17-20H2,1H3,
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: >5 mg/mL
Formpowder
Assay≥98% (HPLC)

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