LINOLEAMIDE

Descriptions

Biochem/physiol Actions

Linoleamide is an endogenous lipid, that stimulates sleep in cats, rats and humans.

Linoleamide is an endogenous primary fatty acid amide (PFAM) signaling lipid that modulates intracellular Ca2+ homeostasis. It has been shown to inhibit of SPCA2, a Golgi secretory pathway Ca(2+)-ATPase that transports ions of Ca2+ and Mn2+ and also to inhibit SPCA1a and the Ca2+-ATPase activity of three sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) pump isoforms. It is thought to be involved in a variety of biological activities including regulation of sleep.

Specifications

Colour	white to beige
Quality Level	100
InChI key	SFIHQZFZMWZOJV-HZJYTTRNSA-N
InChI	1S/C18H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H2,19,20)/b7-6-,10-9-
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: 2 mg/mL, clear
Form	powder
Assay	≥98% (HPLC)