Levocetirizine dihydrochloride, >=98% (HPLC)

Levocetirizine dihydrochloride, >=98% (HPLC)

Stock Code: 3573449
Manufacturer Part No: L7795-10MG
Order Now for 21 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Application


Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.


Biochem/physiol Actions


Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.


Features and Benefits


This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


General description


Levocetirizine dihydrochloride is the R-enantiomer of cetirizine and is used for treating seasonal allergic rhinitis and chronic idiopathic urticaria. The liver metabolizes 14% of levocetirizine and rest is excreted in urine. The response of levocetirizine to histamine is comparatively higher to cetirizine.


Packaging


10, 50 mg in glass bottle

Quality Level100
InChI keyPGLIUCLTXOYQMV-GHVWMZMZSA-N
InChI1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.