Hydroxyfasudil hydrochloride hydrate, >=98% (HPLC), solid

Hydroxyfasudil hydrochloride hydrate, >=98% (HPLC), solid

Stock Code: 3573396
Manufacturer Part No: H4413-25MG
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Application


Hydroxyfasudil hydrochloride hydrate has been used as a ROCK inhibitor to study the role of different signaling pathways in the chemokines CCL19 and CCL21, the CCR7 ligands mediated effects on migratory and prosurvival, in CLL cells.


Biochem/physiol Actions


Rho-kinase inhibitor.


Hydroxyfasudil possessantispastic action. It is an active metabolite of fasudil. Hydroxyfasudil might enhance the dynamics of blood flow and prevent damage caused by neutrophils.


Packaging


5, 25 mg in glass bottle

Colourwhite
Quality Level100
InChI keyXWWFOUVDVJGNNG-UHFFFAOYSA-N
InChI1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H
ManufacturerSIGMA-ALDRICH
CompositionThe two peaks show the equilibrim between the two tautomers
Formsolid
Assay≥98% (HPLC)

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