Hydroxy-Dynasore, >=98% (HPLC)
Biochem/physiol Actions
Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.
Other Notes
Air sensitive.
Packaging
5, 25 mg in glass bottle
| Colour | faintly yellow to dark yellow |
|---|---|
| Quality Level | 100 |
| InChI key | UAXHPUSKEWEOAP-DJKKODMXSA-N |
| InChI | 1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+ |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: >10 mg/mL |
| Form | powder |
| Assay | ≥98% (HPLC) |
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