HAMNO

HAMNO

Stock Code: 3574631
Manufacturer Part No: SML1234-5MG
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£136.50 (exc VAT) per 5MG
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Biochem/physiol Actions


HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. HAMNO binds the N-terminal domain of RPA70 and inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. HAMNO enhances DNA replication stress in cancer cells and slow tumor growth in vivo.


Packaging


5, 25 mg in glass bottle

Colouryellow to orange
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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