GSK690693, >=98% (HPLC)

GSK690693, >=98% (HPLC)

Stock Code: 3574085
Manufacturer Part No: SML0428-5MG
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£242.36 (exc VAT) per 5MG
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Application


GSK690693 has been used in western blotting and immunoprecipitations.


Biochem/physiol Actions


4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol/GSK690693 is a protein kinase B/AKT inhibitor. GSK690693 can prevent growth and apoptosis in acute lymphoblastic leukemia cell lines.


GSK690693 is an ATP competitive, potent pan-AKT kinase inhibitor with IC50 values of 2, 13, and 9 nM against AKT1, 2, and 3, respectively.


Features and Benefits


This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyKGPGFQWBCSZGEL-ZDUSSCGKSA-N
InChI1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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