GGTI-286 DIHYDROCHLORIDE
Biochem/physiol Actions
GGTI-286 is a cell permeable, potent and selective inhibitor of geranylgeranyltransferase I (GGTase I) that selectively disrupts oncogenic K-Ras4B. New study shows that GGTI-286 reduces nuclear localization of β-catenin.
Other Notes
Air sensitive; dessicant.
Packaging
5, 25 mg in glass bottle
| Colour | white to light brown |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Solubility | DMSO: 20 mg/mL, clear |
| Form | powder |
| Assay | ≥90% (HPLC) |
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