FROVATRIPTAN SUCCINATE MONOHYDRATE

FROVATRIPTAN SUCCINATE MONOHYDRATE

Stock Code: 3574711
Manufacturer Part No: SML1291-50MG
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£518.14 (exc VAT) per 50MG
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Biochem/physiol Actions


Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.


During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyCUETXFMONOSVJA-KLQYNRQASA-N
InChI1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥97% (HPLC)

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