ENMD-1068 HYDROCHLORIDE

ENMD-1068 HYDROCHLORIDE

Stock Code: 3574387
Manufacturer Part No: SML1039-5MG
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£138.73 (exc VAT) per 5MG
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Application


ENMD-1068 hydrochloride has been used as a protease-activated receptor 2 (PAR2) antagonist to determine the pathway responsible for paw edema induced by Crotalus durissus terrificus venom serine protease (Cdtsp 2).


Biochem/physiol Actions


ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2). The compound blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice.


ENMD-1068 hydrochloride exhibits anti-angiogenic and anti-inflammatory activities.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityH2O: 25 mg/mL, clear
Formpowder
Assay≥97% (HPLC)

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