Edelfosine, >=95% (HPLC)

Edelfosine, >=95% (HPLC)

Stock Code: 3574042
Manufacturer Part No: SML0332-5MG
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£183.86 (exc VAT) per 5MG
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Application


Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.


Biochem/physiol Actions


Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor.


Features and Benefits


This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


General description


Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyMHFRGQHAERHWKZ-UHFFFAOYSA-N
InChI1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥95% (HPLC)

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