DIPHYLLIN
Application
Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens.
Biochem/physiol Actions
Diphyllin has shown potential to be used in a novel treatment for bone problems characterized by excessive resorption.
Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts.
General description
Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus.
Packaging
5, 25 mg in glass bottle
| Colour | white to light brown |
|---|---|
| Quality Level | 100 |
| InChI key | VMEJANRODATDOF-UHFFFAOYSA-N |
| InChI | 1S/C21H16O7/c1-24-15-6-11-12(7-16(15)25-2)20(22)13-8-26-21(23)19(13)18(11)10-3-4-14-17(5-10)28-9-27-14/h3-7,22H,8-9H2,1-2H3 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: 5 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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