DEFERASIROX

Application

Deferasirox has been used as an iron chelator to test its effect on clofazimine mediated growth inhibition and rescue in Salmonella typhimurium.

Biochem/physiol Actions

Deferasirox is an orally available iron chelator used clinically for reduction of chronic iron overload in diseases such as β-thalassemia.

Deferasirox belongs to the N-substitutedbis-hydroxyphenyl-triazole family of tridentate iron chelators.

Colour	white to beige
InChI key	FMSOAWSKCWYLBB-VBGLAJCLSA-N
InChI	1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,22-23H,(H,27,28)/b19-15-,20-16+
Manufacturer	SIGMA-ALDRICH
Storage Temp.	2-8°C
Solubility	DMSO: 2 mg/mL, clear
Form	powder
Assay	≥98% (HPLC)