CRT0066101 HYDROCHLORIDE

Stock Code: 3575003
Manufacturer Part No: SML1507-5MG
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£135.80 (exc VAT) per 5MG
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Biochem/physiol Actions


CRT0066101 is a very potent inhibitor of Protein Kinase D (PKD) isoforms with IC50 values for PKD-1, -2 and -3 = 1, 2.5 and 2 nM, respecitively. CRT0066101 has been shown to have anticancer activity. CRT0066101 potently inhibits proliferation of PANC-1 pancreatic cells, and blocks migration and invasion of U87MG glioblastoma cells. CRT0066101 has also been shown to decrease growth of primary tumors and metastasis of ER(-) breast cancers.


Packaging


5 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityH2O: 15 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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