CK-666, >=98% (HPLC), powder

Application

CK-666 may be used to study Arp2/3-mediated structural changes in cells.

Biochem/physiol Actions

CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents its movement into active conformation.

CK-666 is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex.

Packaging

5, 25 mg in glass bottle

Colour	white to tan
Quality Level	100
InChI key	UXRKUKRXVWJFER-UHFFFAOYSA-N
InChI	1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22)
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: ≥25 mg/mL
Form	powder
Assay	≥98% (HPLC)