CINACALCET HYDROCHLORIDE

Descriptions

Biochem/physiol Actions

Cinacalcet is a positive allosteric modulator of the Calcium Sensing Receptor (CaSR) that acts as a calcimimetic. It increases the sensitivity of the calcium-sensing receptor to extracellular calcium resulting in a decrease in serum calcium levels.

Specifications

Colour	white to beige
InChI key	QANQWUQOEJZMLL-PKLMIRHRSA-N
InChI	1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: 2 mg/mL, clear
Form	powder
Assay	≥98% (HPLC)