Chromanol 293B, >=98% (HPLC), powder

Chromanol 293B, >=98% (HPLC), powder

Stock Code: 3573309
Manufacturer Part No: C2615-10MG
Order Now for 21 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Application


Chromanol 293B has been used in the inhibition of calcium and cyclic adenosine monophosphate (cAMP)-activated potassium channels in human epithelial cell lines. Chromanol 293B has been used in patch-clamp electrophysiology studies in cardiomyocytes.


Biochem/physiol Actions


Blocker of the slow delayed rectifier K+ current via KCNQ1 channels


Features and Benefits


This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


General description


Chromanol 293B enantiomer is a potent inhibitor of potassium channel protein (KvLQT1). In human atrial myocytes, chromanol 293B inhibits repolarization potassium currents. Chromanol 293B improves glucose-stimulated insulin secretion (GSIS) in pancreas by modulating potassium voltage-gated channel (KCNQ1).


Packaging


10, 50 mg in glass bottle

Colourwhite
Quality Level100
InChI keyHVSJHHXUORMCGK-UONOGXRCSA-N
InChI1S/C15H20N2O4S/c1-5-22(19,20)17(4)13-11-8-10(9-16)6-7-12(11)21-15(2,3)14(13)18/h6-8,13-14,18H,5H2,1-4H3/t13-,14+/m0/s1
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 18 mg/mL
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.