CELIPROLOL HYDROCHLORIDE
Biochem/physiol Actions
Celiprolol is a selective adrenoceptor modulator that acts not only as a selective β1 receptor antagonist, but also as a β2 receptor partial agonist. Because of its of its β2 agonist activity, celiprolol lacks the typical side effects of the beta-blockers, such as bronchoconstriction, depression of left ventricular function, and peripheral vasoconstriction, making it a good candidate for patients with both cardiovascular and pulmonary disease. It is currently being investigated for treatment of vascular Ehlers-Danlos Syndrome (vEDS).
| Colour | white to beige |
|---|---|
| InChI key | VKJHTUVLJYWAEY-UHFFFAOYSA-N |
| InChI | 1S/C20H33N3O4.ClH/c1-7-23(8-2)19(26)22-15-9-10-18(17(11-15)14(3)24)27-13-16(25)12-21-20(4,5)6;/h9-11,16,21,25H,7-8,12-13H2,1-6H3,(H,22,26);1H |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | H2O: 2 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
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