CARPROFEN
Biochem/physiol Actions
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that has been found to have antimicrobial activity. Carprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition with selectivity for COX-2 inhibition, while its antimicrobial activity is less certain. Carprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown carprofen can target the Escherichia coli DNA polymerase III β subunit.
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | PUXBGTOOZJQSKH-UHFFFAOYSA-N |
| InChI | 1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19) |
| Manufacturer | SIGMA-ALDRICH |
| Form | powder |
| Assay | ≥97% (HPLC) |
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