Carboxyamidotriazole, >=98% (HPLC)

Carboxyamidotriazole, >=98% (HPLC)

Stock Code: 3574063
Manufacturer Part No: SML0408-25MG
Order Now for 7 day delivery
£423.43 (exc VAT) per 25MG
Quantity: - +

Biochem/physiol Actions


Carboxyamidotriazole (CAI) is a non-cytotoxic anticancer drug. It exhibits anti-inflammatory properties and reduces the release of proinflammatory cytokines. CAI prevents the proliferation and invasive behavior of a variety of human cancer cell types and endothelial cells in vitro and in vivo. It is used to treat several acute and chronic inflammation models, like adjuvant arthritis and inflammatory bowel diseases (IBD). CAI blocks tumor cell proliferation and stimulates cell apoptosis in vitro.


Carboxyamidotriazole (L-651582) is an orally active calcium channel blocker. Carboxyamidotriazole blocks intracellular and mitochondrial calcium entry and flux, resulting in inhibition of cell proliferation, calcium-release-activated calcium channel (CRAC) function, and maintenance of mitochondrial membrane potential.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyWNRZHQBJSXRYJK-UHFFFAOYSA-N
InChI1S/C17H12Cl3N5O2/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25/h1-6H,7,21H2,(H2,22,27)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 10 mg/mL (clear solution)
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.