Capsaicin, natural

Capsaicin, natural

Stock Code: 3573223
Manufacturer Part No: 360376-1G
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£303.64 (exc VAT) per 1G
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Application


Capsaicin has been used in the development of the isolation methods. It has also been used in the development of enzyme based electrochemical biosensor for the determination of capsaicin using a novel signal amplification strategy.


Biochem/physiol Actions


Capsaicin is used as an important component of oleoresin capsicum or pepper spray. It plays a beneficial role in obesity, cardiovascular and gastrointestinal conditions, several cancers,neurogenic bladder anddermatologic conditions. It is used in the production of spices, chilli sauces and pain-inducing defensive pepper sprays. Capsaicinis also used to manufacture creams to treat diabetic neuropathy, cluster headache, psoriasis, rheumatoid arthritis and reflex sympathetic dystrophy. It is considered as an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1).


Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.


General description


Capsaicin(Zostrix), an alkaloid extract is obtained from hot chili peppers. It is accessible in the form of cream and lotion. Capsaicin is a hydrophobic, instable and pungent white crystalline powder, that has no smell and color. It is produced by mixing a branched-chainfatty acidto vanillylamine in the chili pepper.


Packaging


1 g in glass bottle


250 mg in glass insert

mp62-65 °C (lit.)
InChI keyYKPUWZUDDOIDPM-SOFGYWHQSA-N
InChI1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
ManufacturerSIGMA-ALDRICH
Compositiondihydrocapsaicin, 35%, capsaicin, 65%
Formpowder
Assay63.7% (HPLC)

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