Bikinin, >=98% (HPLC)

Bikinin, >=98% (HPLC)

Stock Code: 3574019
Manufacturer Part No: SML0094-5MG
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Application


Bikinin has been used: as a glycogen synthase kinase-3 (GSK3) inhibitor in Arabidopsis Col-0 seedlings to test its effect on gene expressionas a component of induction medium and as a GSK3 inhibitor to test its effect on mesophyll cells in Arabidopsis leaf discs or cotyledonsas a brassinosteroid agonist to test its effect on the leaf index of R. trichophyllus terrestrial leaves


Biochem/physiol Actions


Bikinin is a strong activator of brassinosteroid (BR) signaling. It is an Arabidopsis GSK-3 Inhibitor, an Arabidopsis SHAGGY-related Kinase Inhibitor, and a GSK-3-like Kinase BIN2 Inhibitor. Bikinin directly inhibits BIN2 (group II GSK3s) by interfering with ATP binding. Bikinin is specific toward a subset of Arabidopsis GSK3 kinases including BIN2 and ASK α, γ, ε, ι, and θ.


Packaging


5, 25 mg in glass bottle

Colourwhite to tan
Quality Level100
InChI keyXFYYQDHEDOXWGA-UHFFFAOYSA-N
InChI1S/C9H9BrN2O3/c10-6-1-2-7(11-5-6)12-8(13)3-4-9(14)15/h1-2,5H,3-4H2,(H,14,15)(H,11,12,13)
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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