Aurothioglucose hydrate, >=97% (titration)

Aurothioglucose hydrate, >=97% (titration)

Stock Code: 3573238
Manufacturer Part No: A0606-5MG
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£250.71 (exc VAT) per 5MG
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Application


Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.


Biochem/physiol Actions


Aurothioglucose, a gold compound used clinically to treat rheumatoid arthritis, has recently been found to be a potent PKCiota-Par6 interaction inhibitor, with an IC50 approximately 1 µM. Disruption of this interaction disrupts a rac1 signaling pathway that is required for transformed growth in non-small-cell lung cancer.


Features and Benefits


This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keySGVIEHTYEMEDRR-PKXGBZFFSA-M
InChI1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 5 mg/mL, clear
Formpowder
Assay≥96% (titration)

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