ALMOTRIPTAN MALATE

Descriptions

Application

Almotriptan is a serotonin 5HT-1B/1D-receptor agonist; antimigraine.

Almotriptan at an oral dose of 12.5mg, is recommended to be safe for treating migraine.

Biochem/physiol Actions

Almotriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Almotriptan has low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower. Affinity for 5-HT(7) and 5-HT(1A) receptors was approximately 40 and 60 times lower than that for 5-HT(1B/1D) receptors, respectively.

Specifications

Colour	white to beige
Quality Level	100
InChI key	QHATUKWEVNMHRY-UHFFFAOYSA-N
InChI	1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,
Manufacturer	SIGMA-ALDRICH
Solubility	H2O: 10 mg/mL, clear
Form	powder
Assay	≥98% (HPLC)