AEM1

AEM1

Stock Code: 3575082
Manufacturer Part No: SML1556-25MG
Order Now for 7 day delivery
£502.82 (exc VAT) per 25MG
Quantity: - +

Biochem/physiol Actions


AEM1 (ARE expression modulator 1) is also a selective inhibitor of sirtuin 2, which is a protein deacetylase mediated by NAD+. Sirtuin 2 supports tumor cell proliferation, thus its inhibition stimulates cell death in tumors.


AEM1 is a potent inhibitor of deregulated Nrf2 transcriptional activity. AEM1 broadly decreases the expression of NRF2 controlled genes and sensitizes A549 cells to various chemotherapeutic agents.


Packaging


5, 25 mg in glass bottle

Colourwhite to light brown
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.