AC-41848 hydrate, >=98% (HPLC), solid

Descriptions

Application

AC-41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist.

Biochem/physiol Actions

AC-41848 is a potent, cell permeable, subtype selective retinoic acid receptor RARγ agonist. AC-41848 has high selectivity (92%) for RARγ. EC₅₀= 5.9 µM.

Features and Benefits

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 20 mg in glass bottle

Specifications

Quality Level	100
InChI key	FPOBEBBUBSFIIA-UHFFFAOYSA-M
InChI	1S/C21H21Cl2N2.BrH.H2O/c22-18-11-10-17(19(23)13-18)14-24-15-20(16-7-3-1-4-8-16)25-12-6-2-5-9-21(24)25;;/h1,3-4,7-8,10-11,13,15H,2,5-6,9,12,14H2;1H;1H2/q+1;;/p-
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: ~14 mg/mL, H2O: >5 mg/mL
Form	solid
Assay	≥98% (HPLC)