Biochem/physiol Actions
A66 is a potent and highly selective inhibitor of the phosphoinositide 3-kinase (PI3K) catalytic subunit p110α with an?IC50 of 32 nM and >100 fold selectivity for p110α over other class-I PI3K isoforms.
Packaging
5, 25 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | HBPXWEPKNBHKAX-NSHDSACASA-N |
| InChI | 1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | DMSO: 20 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
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