A01 (Smurf 1 Inhibitor)

A01 (Smurf 1 Inhibitor)

Stock Code: 3574867
Manufacturer Part No: SML1404-25MG
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£401.14 (exc VAT) per 25MG
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Biochem/physiol Actions


A01 is a high affinity selective inhibitor of E3 ubiquitin-protein ligase Smurf1 (Smad ubiquitination regulatory factor-1) that disturbs Smurf1-Smad1/5 interaction and blocks Smurf1 mediated Smad1/5 ubiquitination. A01 increases responsiveness to BMP-2 in myoblasts and osteoblasts.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyQFYLTUDRXBNZFQ-UHFFFAOYSA-N
InChI1S/C22H20ClF3N4O3S/c1-15-8-9-27-30(15)17-4-2-16(3-5-17)21(31)28-10-12-29(13-11-28)34(32,33)18-6-7-20(23)19(14-18)22(24,25)26/h2-9,14H,10-13H2,1H3
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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