A-779 TRIFLUROACETATE SALT
Biochem/physiol Actions
A-779 (D-Ala7-Ang-(1-7)) is a potent and selective antagonist of angiotensin (1-7), an endogenous peptide that acts through activation of a non-AT1, non-AT2 receptor, Mas, and opposes the activity of angiotensin. A-779 has an IC50 of 0.3 nM for Mas with negligible affinity for either AT1R or AT2R.
This blocking angiotensin action affects cardiovascular function.
Packaging
5, 25 mg in glass bottle
| Colour | white to off-white |
|---|---|
| Quality Level | 100 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Form | lyophilized powder |
| Assay | ≥98% (HPLC) |
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