(R)-PFI-2

(R)-PFI-2

Stock Code: 3574873
Manufacturer Part No: SML1408-25MG
Order Now for 7 day delivery
£888.64 (exc VAT) per 25MG
Quantity: - +

Biochem/physiol Actions


(R)-PFI-2 is a histone-lysine N-methyltransferase (HKMT) inhibitor selective for SETD7 (also known as SET9). (R)-PFI-2 has an IC50 value of 2 nM and 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. For full characterization details, please visit the PFI-2 probe summary on the Structural Genomics Consortium (SGC) website.(S)-PFI-2, an enantiomer of (R)-PFI-2, is used as a negative control. (S)-PFI-2 is available from Sigma. To learn more about and purchase (S)-PFI-2, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc


Features and Benefits


(R)-PFI-2 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.


This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


Other Notes


(R)-PFI-2 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the (R)-PFI-2 probe summary on the Chemical Probes Portal website.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyZADKZNVAJGEFLC-ZMBIFBSDSA-N
InChI1S/C23H25F4N3O3S.ClH/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27;/h3-5,10,12-13,21,28-29H,1-2,6-9
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 10 mg/mL, clear (warmed)
Formpowder
Assay≥97% (HPLC)

There are no downloads for this product.