(2S)-Hypusine dihydrochloride

(2S)-Hypusine dihydrochloride

Stock Code: 3574542
Manufacturer Part No: SML1158-25MG
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£612.86 (exc VAT) per 25MG
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Biochem/physiol Actions


(2S)-Hypusine is an unusual amino acid found only in eukaryotic translation initiation factor 5A (eIF5A) and a similar protein in archaebacteria. (2S)-Hypusine is formed by posttranslational modification of a lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. There is increasing interest in the polyamine-hypusine axis and eIF5A, its a role in cell growth and differentiation, and a recent paper on the polyamine-hypusine axis as a potential new tumour suppressor network.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyUTSZZUVUESAPQD-AHBBCRTASA-N
InChI1S/C10H23N3O3.2ClH/c11-5-4-8(14)7-13-6-2-1-3-9(12)10(15)16;;/h8-9,13-14H,1-7,11-12H2,(H,15,16);2*1H/t8?,9-;;/m0../s1
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 15 mg/mL, clear
Formpowder
Assay≥95% (HPLC)

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