(Z)-Guggulsterone, >=89% (HPLC), powder
Biochem/physiol Actions
(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.
| Colour | light yellow |
|---|---|
| Quality Level | 200 |
| InChI key | WDXRGPWQVHZTQJ-OSJVMJFVSA-N |
| InChI | 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1 |
| Manufacturer | SIGMA-ALDRICH |
| Impurities | ≤5.4% E-form |
| Form | powder |
| Assay | ≥89% (HPLC) |
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