[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

Stock Code: 3591638
Manufacturer Part No: L4513-25MG
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Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt

Application

[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate has been used: as an luteinizing hormone-releasing hormone (LHRH) agonist to synchronize a cohort of females ratsto synchronize naturally cycling rats to induce ovulation as a gonadotropin-releasing hormone (GnRH) analogue and as a supplement in Galap extender to dilute qualified ejaculate

Biochem/physiol Actions

Potent LH-RH agonist in rats and mice; reversibly delays sexual maturation in rats, stimulates spawning activity in fish. GnRH ( gonadotropin-releasing hormone, Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Quality Level100
InChI keyYEEHIOYEWOESQR-PFHUABGLSA-N
InChI1S/C56H78N16O12.C2H4O2.H2O/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15-
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formpowder
Assay≥97% (HPLC)

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