Hemoglobin from bovine blood, suitable for protease substrate, substrate powder

Descriptions

Application

Hemoglobin from bovine blood has been used as a substrate in cathepsin D activity assay. It has also been used to measure the activity of acid proteases (pepsin-like) in the stomach extract.

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Bovine hemoglobin is used in the production ofhemoglobin-vesicles (HbV).Ithas high thermal stability and high oxygen affinity when compared to humanhemoglobin.Bovine hemoglobin interactswithsynthetic and azo dyes.Polymerized forms of bovine hemoglobin are used to treat autoimmunehemolytic anemia.

Oxygen transporter. The Fe²⁺/Fe³⁺ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

General description

Hemoglobin is the major component of red blood cells and is responsible for their red color. Its normal concentration in erythrocytes is 34%.Hemoglobin is a globular protein with ? and ? chains with every 141 and 146 amino acidsrespectively. It exists as a tetramer with each monomer having heterocyclic porphyrin ring with iron constituting the heme.

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

Packaging

25, 100 g in glass bottle

1 kg in poly drum

Preparation Note

Prepared from washed, lysed and dialyzed erythrocytes.

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	Manufacturer	Storage Temp.	Suitability	Solubility	Form	Price	Quantity
3591421	Hemoglobin from bovine blood, suitable for protease substrate, substrate powder	300	SIGMA-ALDRICH	2-8°C	suitable for protease substrate	H2O: soluble 20 mg/mL	substrate powder	£223.93 (exc VAT) per 100G	- +
3591422	Hemoglobin from bovine blood, suitable for protease substrate, substrate powder	300	SIGMA-ALDRICH	2-8°C	suitable for protease substrate	H2O: soluble 20 mg/mL	substrate powder	Click Add to Quote for price and delivery	- +
3591423	Hemoglobin from bovine blood, suitable for protease substrate, substrate powder	300	SIGMA-ALDRICH	2-8°C	suitable for protease substrate	H2O: soluble 20 mg/mL	substrate powder	£65.96 (exc VAT) per 25G	- +