Valinomycin, >=98.0% (TLC)

Application

Valinomycin has been used as an internal standard in the cytotoxicity assay for the detection of cereulide produced by emetic Bacillus cereus. It has also been used in the measurement of the electrogenicity of bile salt/H+ antiport in Escherichia coli.

Biochem/physiol Actions

K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.

Valinomycin affects the ion transport behavior of mitochondrial systems.

General description

Chemical structure: peptide

Valinomycinis a neutral cyclic dodecadepsipeptide antibiotic, that has a 36-member ring.

Other Notes

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Code Description Quality Level mp InChI key InChI Manufacturer Form Assay Price Quantity
3589364 Valinomycin, >=98.0% (TLC) 200 187-190 °C FCFNRCROJUBPLU-RPUZOQEISA-N 1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)4 SIGMA-ALDRICH powder ≥99.0% (TLC)
£747.96 (exc VAT) per 100MG
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3589365 Valinomycin, >=98.0% (TLC) 200 187-190 °C FCFNRCROJUBPLU-RPUZOQEISA-N 1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)4 SIGMA-ALDRICH powder ≥99.0% (TLC)
£120.62 (exc VAT) per 10MG
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3589366 Valinomycin, >=98.0% (TLC) 200 187-190 °C FCFNRCROJUBPLU-RPUZOQEISA-N 1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)4 SIGMA-ALDRICH powder ≥99.0% (TLC)
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