[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt

Application

[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate has been used: as an luteinizing hormone-releasing hormone (LHRH) agonist to synchronize a cohort of females ratsto synchronize naturally cycling rats to induce ovulation as a gonadotropin-releasing hormone (GnRH) analogue and as a supplement in Galap extender to dilute qualified ejaculate

Biochem/physiol Actions

Potent LH-RH agonist in rats and mice; reversibly delays sexual maturation in rats, stimulates spawning activity in fish. GnRH ( gonadotropin-releasing hormone, Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Code Description Quality Level InChI key InChI Manufacturer Storage Temp. Form Assay Price Quantity
3591637 [des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder 100 YEEHIOYEWOESQR-PFHUABGLSA-N 1S/C56H78N16O12.C2H4O2.H2O/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15- SIGMA-ALDRICH −20°C powder ≥97% (HPLC)
£114.77 (exc VAT) per 1MG
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3591638 [des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder 100 YEEHIOYEWOESQR-PFHUABGLSA-N 1S/C56H78N16O12.C2H4O2.H2O/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15- SIGMA-ALDRICH −20°C powder ≥97% (HPLC)
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3591639 [des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder 100 YEEHIOYEWOESQR-PFHUABGLSA-N 1S/C56H78N16O12.C2H4O2.H2O/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15- SIGMA-ALDRICH −20°C powder ≥97% (HPLC)
£424.82 (exc VAT) per 5MG
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