Insulin Chain B Oxidized from bovine pancreas, >=80% (HPLC), powder
Amino Acid Sequence
Phe-Val-Asn-Gln-His-Leu-Cys(SO3H)-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys(SO3H)-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala
Application
Insulin Chain B Oxidized from bovine pancreas has been used:as a matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry (MS) calibration standardin electrochemical impedance spectroscopy and quartz crystal nanobalance (EQCN) studies of insulin adsorption on platinumas an internal standard to quantify insulin chain B residue in protein samples
Biochem/physiol Actions
Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids. It inhibits the breakdown of glycogen, protein, and fat. The β chain is a substrate for carboxypeptidase Y.
General description
Insulin is made up of two polypeptide chains (A and B) linked together by two disulfide linkages. Chain A and B are composed of 21 amino acids and 30 amino acids, respectively.
Preparation Note
Prepared by modification of Sanger, F., et al.
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