Arg-Gly-Asp, >=97% (TLC)

Amino Acid Sequence

Arg-Gly-Asp

Application

Arg-Gly-Asp has been used:to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogelin adhesion assayin inhibition assay to confirm the ?1-integrin-dependency of cell adhesionin textile fabrication and RGD textile functionalizationto engineer a population of human dermal fibroblasts with impaired migrationto modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)in the cell culture of human mammary epithelial cells

Biochem/physiol Actions

Primary sequence involved with the binding of proteins to cell surfaces

General description

Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A8052.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Tripeptide from the cell-attachment domain of fibronectin

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Code Description Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3589632 Arg-Gly-Asp, >=97% (TLC) 200 IYMAXBFPHPZYIK-BQBZGAKWSA-N 1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1 SIGMA-ALDRICH powder ≥97% (TLC)
£201.25 (exc VAT) per 10MG
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3589633 Arg-Gly-Asp, >=97% (TLC) 200 IYMAXBFPHPZYIK-BQBZGAKWSA-N 1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1 SIGMA-ALDRICH powder ≥97% (TLC)
£40.38 (exc VAT) per 1MG
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3589634 Arg-Gly-Asp, >=97% (TLC) 200 IYMAXBFPHPZYIK-BQBZGAKWSA-N 1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1 SIGMA-ALDRICH powder ≥97% (TLC)
£114.75 (exc VAT) per 5MG
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