Melphalan, powder

Descriptions

Application

Melphalan has been used as a drug along with HDAC-inhibitor JNJ-26481585 to treat multiple myeloma (MM) in cell lines and as a chemotherapeutic agent for breast cancer cell line.

Biochem/physiol Actions

In rat, melphalan in isolated lung perfusion (ILP) functions as a potent therapeutics for sarcomatous pulmonary metastases. It forms DNA intrastrand crosslinks by bifunctional alkylation in 5?-GGC sequences. Melphalan acts as a bone-marrow depressant and is implicated in the treatment of multiple myeloma and ovarian cancer.

Melphalan is an antineoplastic agent.

General description

Melphalan also known as L-phenylalanine mustard is an alkylating agent. It belongs to the class of nitrogen mustards, which act as chemotherapeutic agents.

Packaging

1 g in glass bottle

100, 250 mg in glass bottle

Specifications

No detailed specifications are available for this product.

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Code	Description	Colour	Quality Level	InChI key	InChI	Manufacturer	Form	Price
3591743	Melphalan, powder	white	200	SGDBTWWWUNNDEQ-LBPRGKRZSA-N	1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1	SIGMA-ALDRICH	powder	You need to be logged in to see prices.
3591744	Melphalan, powder	white	200	SGDBTWWWUNNDEQ-LBPRGKRZSA-N	1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1	SIGMA-ALDRICH	powder	You need to be logged in to see prices.
3591745	Melphalan, powder	white	200	SGDBTWWWUNNDEQ-LBPRGKRZSA-N	1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1	SIGMA-ALDRICH	powder	You need to be logged in to see prices.