gamma-Globulins from human blood, >=99% (electrophoresis)

gamma-Globulins from human blood, >=99% (electrophoresis)

Application

?-Globulins from human blood have been used for the blocking step in cytometric bead array It has also been used as a standard for ?-globulin measurement in cerebrospinal fluid (CSF).

?-globulins were used to study a micro-method for measuring total protein in cerebrospinal fluid by using benzethonium chloride in microtiter plate wells. It was used in the measurement of protein in tannin-protein precipitates using ninhydrin. It was also used to study the blood distribution of levocetirizine, a new non-sedating histamine H1-receptor antagonist, in humans.

Biochem/physiol Actions

Immunoglobulins are key regulators of the immune system and are produced in response to antigens. They protect our bodies against bacteria, viruses, and fungi. Immunoglobulins are involved in the activation of the complement system, opsonization of microbes for phagocytosis, neutralization of toxins and viruses, and inhibition of the attachment of microbes to mucosal surfaces. Immunodeficiency can lead to recurrent infectious diseases.

General description

?-Globulins are immunoglobulins and occur in five classes, namely: IgG, IgM, IgA, IgD, and IgE. These are glycoproteins that are antibodies produced by plasma cells. The immunoglobulins are heterogeneous molecules made up of four polypeptide chains (two light chains and two heavy chains) linked together by disulfide bonds. The antigen-binding site is present at the nitrogen terminal. 20% of the protein in plasma are immunoglobulins.

Packaging

250 mg in poly bottle

1, 5, 10, 25 g in poly bottle

Preparation Note

Prepared from Cohn Fraction II, III

No detailed specifications are available for this product.

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Code Description Quality Level Manufacturer Storage Temp. Impurities Solubility Form Assay Price Quantity
3591317 gamma-Globulins from human blood, >=99% (electrophoresis) 300 SIGMA-ALDRICH 2-8°C ≤4% NaCl, HIV, HCV and HBsAg, source material tested negative 0.9% NaCl: soluble 50 mg/mL powder ≥99% (electrophoresis)
£1,072.14 (exc VAT) per 10G
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3591318 gamma-Globulins from human blood, >=99% (electrophoresis) 300 SIGMA-ALDRICH 2-8°C ≤4% NaCl, HIV, HCV and HBsAg, source material tested negative 0.9% NaCl: soluble 50 mg/mL powder ≥99% (electrophoresis)
£219.86 (exc VAT) per 1G
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3591319 gamma-Globulins from human blood, >=99% (electrophoresis) 300 SIGMA-ALDRICH 2-8°C ≤4% NaCl, HIV, HCV and HBsAg, source material tested negative 0.9% NaCl: soluble 50 mg/mL powder ≥99% (electrophoresis)
£68.13 (exc VAT) per 250MG
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3591320 gamma-Globulins from human blood, >=99% (electrophoresis) 300 SIGMA-ALDRICH 2-8°C ≤4% NaCl, HIV, HCV and HBsAg, source material tested negative 0.9% NaCl: soluble 50 mg/mL powder ≥99% (electrophoresis)
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3591321 gamma-Globulins from human blood, >=99% (electrophoresis) 300 SIGMA-ALDRICH 2-8°C ≤4% NaCl, HIV, HCV and HBsAg, source material tested negative 0.9% NaCl: soluble 50 mg/mL powder ≥99% (electrophoresis)
£627.00 (exc VAT) per 5G
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