Tetraethylammonium chloride, >=98% (titration)

Tetraethylammonium chloride, >=98% (titration)

Application

Tetraethylammonium chloride (TEAC) has been used:used for inhibition of peroxynitrite induced relaxation in rat aorta ringsas a pharmacological blocker of K+ current and Ca2+ induced K+ current in antennal lobe neuronsfor the induction of TEAC sensitive currents in cochlear inner hair cells digested with proteolytic enzymes and analyze its properties

Biochem/physiol Actions

Blocks K+ channels; blocks nicotinic acetylcholine neurotransmission by blocking the receptor-mediated K+ currents.

Tetraethylammonium chloride (TEAC) blocks K+ channels non-specifically. In rat aorta rings, tetraethylammonium inhibits relaxation induced by peroxynitrite. It blocks nicotinic acetylcholine neurotransmission by blocking the receptor-mediated K+ currents. TEAC can increase the contractility and mobility of colon and rectum and is a therapeutic option for Hirschsprung?s disease patients. TEAC reduces the inflammatory responses, improves cardiac, vascular and hemodynamic properties during early sepsis in animals. TEAC has cytotoxic and anti-proliferative potential and induces apoptosis in glioma cells by downregulating B-cell lymphoma-2 (Bcl-2) and upregulating Bcl-2 associated X (Bax).

Caution

moisture sensitive, handle under argon

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3593729 Tetraethylammonium chloride, >=98% (titration) white to light yellow 200 YMBCJWGVCUEGHA-UHFFFAOYSA-M 1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1 SIGMA-ALDRICH powder ≥98% (titration)
£165.75 (exc VAT) per 100G
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3593730 Tetraethylammonium chloride, >=98% (titration) white to light yellow 200 YMBCJWGVCUEGHA-UHFFFAOYSA-M 1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1 SIGMA-ALDRICH powder ≥98% (titration)
£58.22 (exc VAT) per 25G
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