Bradykinin Fragment 1-5, >=97% (HPLC)

Bradykinin Fragment 1-5, >=97% (HPLC)

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe

Biochem/physiol Actions

The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Code Description Quality Level InChI key InChI Manufacturer Storage Temp. Form Assay Price Quantity
3589691 Bradykinin Fragment 1-5, >=97% (HPLC) 200 USSUMSBPLJWFSZ-UHFFFAOYSA-N 1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9 SIGMA-ALDRICH −20°C powder ≥97% (HPLC)
£78.98 (exc VAT) per 1MG
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3589692 Bradykinin Fragment 1-5, >=97% (HPLC) 200 USSUMSBPLJWFSZ-UHFFFAOYSA-N 1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9 SIGMA-ALDRICH −20°C powder ≥97% (HPLC)
£273.00 (exc VAT) per 5MG
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