NS 1619, powder

Biochem/physiol Actions

NS 1619 is a selective large conductance Ca2+-activated K+-channel activator. The compound is known for its vasodilating and anti-proliferative properties. It is studied that NS 1619 can protect cardiac muscle against ischemia and reperfusion injury.

NS-1619 can promote the formation of mitochondrial reactive oxygen species (ROS) in cardiac myocytes. It enhances the formation of ROS in cultured brain slices. NS-1619 has the ability to enhance HO-1 activity in wild-type (WT) animals.

Caution

Photosensitive

Packaging

5, 25 mg in glass bottle

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Code Description Colour InChI key InChI Manufacturer Solubility Form Price Quantity
3591845 NS 1619, powder white YLFMCMWKHSDUCT-UHFFFAOYSA-N 1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25) SIGMA-ALDRICH DMSO: 5.3 mg/mL, ethanol: 26.6 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL, 0.1 M NaOH: 5.2 mg/mL, H2O: insoluble powder
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3591846 NS 1619, powder white YLFMCMWKHSDUCT-UHFFFAOYSA-N 1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25) SIGMA-ALDRICH DMSO: 5.3 mg/mL, ethanol: 26.6 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL, 0.1 M NaOH: 5.2 mg/mL, H2O: insoluble powder
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