![[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder](/images/1000x1000/3591638.jpg "[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder")
[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder
Amino Acid Sequence
Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt
Application
[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate has been used: as an luteinizing hormone-releasing hormone (LHRH) agonist to synchronize a cohort of females ratsto synchronize naturally cycling rats to induce ovulation as a gonadotropin-releasing hormone (GnRH) analogue and as a supplement in Galap extender to dilute qualified ejaculate
Biochem/physiol Actions
Potent LH-RH agonist in rats and mice; reversibly delays sexual maturation in rats, stimulates spawning activity in fish. GnRH ( gonadotropin-releasing hormone, Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
| Quality Level | 100 |
|---|---|
| InChI key | YEEHIOYEWOESQR-PFHUABGLSA-N |
| InChI | 1S/C56H78N16O12.C2H4O2.H2O/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15- |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Form | powder |
| Assay | ≥97% (HPLC) |
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